abstract：OBJECTIVE:The current review describes how the health status profile of people with fibromyalgia (FM) compares to that of people in the general population and patients with other health conditions. METHODS:A review of 37 studies of FM that measured health status with the 36-item Medical Outcomes Study Short-Form Healt...

journal_title：International journal of clinical practice

authors： Hoffman DL,Dukes EM

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Systemic lupus erythematosus (SLE) is a heterogenous disease with complex pathogenesis. AIM:In this review, we summarise recent progress in the understanding of SLE pathogenesis and discuss implications for the treatment of SLE patients using standard and experimental medications. CONCLUSIONS:The discovery...

journal_title：International journal of clinical practice

authors： Ermann J,Bermas BL

更新日期：2007-12-01 00:00:00

abstract：:The aim of this review was to outline current forms of surgical simulation and methods of assessing technical skills using these forms of simulation. To review this subject, a literature search was done using key words 'assessment', 'simulation', 'surgery', 'technical skills' and 'virtual reality'. Simulation in surge...

journal_title：International journal of clinical practice

authors： Sarker SK,Patel B

更新日期：2007-12-01 00:00:00

abstract：AIMS:This review aims at analysing the published literature on chemotherapy for hormone-refractory prostate cancer (HRPC) to provide recommendations for the treatment of this important patient group. METHODS:The information for this review was compiled using the PubMed and Medline databases and the Proceedings of the ...

journal_title：International journal of clinical practice

authors： Chowdhury S,Burbridge S,Harper PG

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:This review examines the available data on the efficacy of selective serotonin reuptake inhibitors (SSRIs) and serotonin-noradrenaline reuptake inhibitors (SNRIs) for treating the commonly missed climacteric symptoms of menopause. DISCUSSION:Although some women may pass through the menopausal transition phas...

journal_title：International journal of clinical practice

authors： Warren MP

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Substantial residual cardiovascular risk persists despite effective LDL lowering treatment in populations at elevated risk for adverse cardiovascular outcomes. Low HDL cholesterol is an independent cardiovascular risk factor and occurs in about one-third of patients treated for dyslipidaemia in Europe. Moreo...

journal_title：International journal of clinical practice

authors： Vogt A,Kassner U,Hostalek U,Steinhagen-Thiessen E

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Budesonide/formoterol is an effective treatment for both asthma and chronic obstructive pulmonary disease. This study compared the efficacy and safety of a novel hydrofluoroalkane (HFA) pressurised metered-dose inhaler (pMDI) formulation of budesonide/formoterol with that of budesonide pMDI and budesonide/fo...

journal_title：International journal of clinical practice

authors： Morice AH,Peterson S,Beckman O,Osmanliev D

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:This study compared effectiveness of rosuvastatin (RSV) with other statins on lowering LDL-C and LDL-C goal attainment among Medicare-eligible patients (age >or= 65 years) and patients with age < 65 years treated in usual clinical practice to provide evidence of real-world effectiveness of statins. METHODS:R...

journal_title：International journal of clinical practice

authors： Fox KM,Gandhi SK,Ohsfeldt RL,Blasetto JW,Davidson MH

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Stroke risk is heightened among patients who have had a primary stroke or transient ischaemic attack (TIA). The primary care physician is in the best position to monitor these patients for stroke recurrence. Because stroke recurrence can occur shortly after the primary event, guidelines recommend initiating ...

journal_title：International journal of clinical practice

authors： Kirshner HS

更新日期：2007-10-01 00:00:00

abstract：:Pharmacological treatment of hypertension represents a cost-effective way for preventing cardiovascular and renal complications. To benefit maximally from antihypertensive treatment blood pressure (BP) should be brought to below 140/90 mmHg in every hypertensive patient, and even lower (< 130/80 mmHg) if diabetes or r...

journal_title：International journal of clinical practice

authors： Struijker-Boudier HA,Ambrosioni E,Holzgreve H,Laurent S,Mancia G,Ruilope LM,Waeber B

更新日期：2007-09-01 00:00:00

abstract：:Hyperthyrotropinaemia, in which normal levels of T4 occur in association with raised thyroid stimulating hormone (TSH), is usually picked up on neonatal screening. High TSH level can continue for a long time in some of the cases. There is no consensus concerning the follow-up or treatment plan for hyperthyrotropinaemi...

journal_title：International journal of clinical practice

authors： Demirel F,Bideci A,Camurdan MO,Cinaz P

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Although mild asthmatics form the majority of asthma sufferers, there is a relative paucity of evidence-based treatment compared with severe asthmatics. OBJECTIVE:We have performed an up-to-date review of the literature on therapy in this group of patients who form an overlooked but important majority. Pote...

journal_title：International journal of clinical practice

authors： Koh MS,Irving LB

更新日期：2007-08-01 00:00:00

abstract：AIMS:This was a post hoc analysis to determine whether baseline severity of depression influenced the efficacy of duloxetine in treating major depressive disorder (MDD) and to better characterise the symptom response profile for duloxetine in patients with mild, moderate or more severe depression. METHODS:Data were po...

journal_title：International journal of clinical practice

authors： Shelton RC,Prakash A,Mallinckrodt CH,Wohlreich MM,Raskin J,Robinson MJ,Detke MJ

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:The objectives of this study were to compare the performance indicators of risk-adjustment models based on administrative and clinical data in Korea, and to assess whether administrative data alone is useful for comparing quality of care. METHODS:Outcome was defined as death within 30 days of discharge. For ...

journal_title：International journal of clinical practice

authors： Park HK,Yoon SJ,Ahn HS,Ahn LS,Seo HJ,Lee SI,Lee KS

更新日期：2007-07-01 00:00:00

abstract：:Day-case and short-stay thyroid surgery is carried out routinely around the world. In the UK longer postoperative stay is usually advocated to circumvent/identify potentially catastrophic complications following thyroidectomy. In the current climate of the National Health Service with focus on patient-centred service,...

journal_title：International journal of clinical practice

authors： Mirnezami R,Sahai A,Symes A,Jeddy T

更新日期：2007-07-01 00:00:00

abstract：:Breast cancer (BC) accounts for >30% of all new cancer patients among women but with increased early detection rates and improved adjuvant therapy, the 5-year survival rate presently reaches >85%. As the number of BC survivors increases, research into the sequelae of the cancer and its treatment on quality of life is ...

journal_title：International journal of clinical practice

authors： Gomide LB,Matheus JP,Candido dos Reis FJ

更新日期：2007-06-01 00:00:00

abstract：:The objective of this study was to investigate the impact of rivastigmine therapy on attention, apathy, anxiety and agitation in patients with mild-to-moderate Alzheimer's disease (AD) in a real-world clinical setting. Patients with mild-to-moderate AD were enrolled in the study by physicians across Canada. They were ...

journal_title：International journal of clinical practice

authors： Gauthier S,Juby A,Rehel B,Schecter R

更新日期：2007-06-01 00:00:00

abstract：:Despite huge advances in terms of the impact of antiretroviral therapy on HIV-related morbidity and mortality patients continue to fail therapy. We discuss the reasons why failure occurs including primary or transmitted resistance, poor adherence, toxicity and drug potency. We performed a review of PubMed, Medline and...

journal_title：International journal of clinical practice

authors： Waters L,Nelson M

更新日期：2007-06-01 00:00:00

abstract：:Zoledronic acid inhibits bone resorption for up to 12 months. It is not known whether the duration of this antiresorptive effect extends beyond this period of time. The aim of this study was to evaluate the changes in bone turnover at 12 months (T12) and 18 months (T18) after a single injection of 4 mg of zoledronic a...

journal_title：International journal of clinical practice

authors： Borba VZ,Paz-Filho G,Kulak CA,Seibel MJ,Bilezikian JP

更新日期：2007-06-01 00:00:00

abstract：:Indiplon is a novel non-benzodiazepine sedative-hypnotic that modulates the GABAA receptor complex. It appears to be more selective for the alpha1-receptor subunit, associated with sedation, than other hypnotics. Two different formulations of indiplon have been developed: an immediate release (IR) version targeting sl...

journal_title：International journal of clinical practice

authors： Lankford A,Ancoli-Israel S

更新日期：2007-06-01 00:00:00

abstract：:An increasing number of patients aged>or=70 years are presenting for elective non-cardiac surgery. We undertook this study to: (i) compare the nature and distribution of cardiovascular disease (CVD) risk factors in an at risk population of patients aged>or=70 years undergoing elective surgery compared with a younger a...

journal_title：International journal of clinical practice

authors： Naughton C,Feneck RO

更新日期：2007-05-01 00:00:00

abstract：:Paliperidone, the 9-hydroxy metabolite of risperidone, was approved on 20 December, 2006 by the US Food and Drug Administration for the treatment of schizophrenia. It is also being tested for the treatment of bipolar mania. An on-line query of http://www.pubmed.gov and http://www.clinicaltrials.gov for 'paliperidone' ...

journal_title：International journal of clinical practice

authors： Citrome L

更新日期：2007-04-01 00:00:00

abstract：:To investigate the influence of the S447X variant in lipoprotein lipase (LPL) gene on the response rate to therapy with the thiazolidinedione pioglitazone. A total of 113 diabetic patients were treated with pioglitazone 30 mg for 10 weeks. Response to the pioglitazone treatment was defined by either a >10% relative re...

journal_title：International journal of clinical practice

authors： Wang G,Wang X,Zhang Q,Ma Z

更新日期：2007-04-01 00:00:00

abstract：:A high prevalence of newly detected diabetes mellitus (DM) and impaired glucose tolerance (IGT) has been reported in patients with acute myocardial infarction (AMI) and no previous diagnosis of DM. However, the prevalence of newly detected DM is grossly underestimated by using fasting plasma glucose (FPG). We determin...

journal_title：International journal of clinical practice

authors： Jessani S,Gangopadhyay K,Patel JV,Lip GY,Millane T

更新日期：2007-04-01 00:00:00

abstract：:Tissue inflammation has been linked to cancer in several disease models. We tested the association between chronic inflammation and prostate cancer (PCa), as well as high-grade prostatic intraepithelial neoplasia (HGPIN), in prostatic needle biopsy specimens. Tissues from 4526 men, who underwent systematic ultrasound-...

journal_title：International journal of clinical practice

authors： Karakiewicz PI,Benayoun S,Bégin LR,Duclos A,Valiquette L,McCormack M,Bénard F,Saad F,Perrotte P

更新日期：2007-03-01 00:00:00

abstract：:Age-related macular degeneration (AMD) is the leading cause of adult blindness among individuals aged 50 and older in the Western world, with the neovascular form of AMD responsible for the most severe and rapid visual loss. Although monotherapy with currently available treatments can slow the rate of loss of vision i...

journal_title：International journal of clinical practice

authors： Kaiser PK,Do DV

更新日期：2007-03-01 00:00:00

abstract：:Prostate cancer remains a most intriguing condition, which poses unique challenges. On reviewing recent literature on localised disease (confined within the capsule T1 or T2, N0, M0), it would seem that it is over treated, resulting in significant morbidity. We now have strong evidence, however, that there can be mort...

journal_title：International journal of clinical practice

authors： Hodgson D,Acher P,Cahill D

更新日期：2007-02-01 00:00:00

abstract：:Systolic heart failure (SHF) is associated with increased morbidity and mortality. Beta-blockers (BB) were shown to provide mortality benefit in patients with SHF, and currently indicated in all stages of patients with SHF. We evaluated the factors influencing the prescription of BBs at discharge in patients hospitali...

journal_title：International journal of clinical practice

authors： Yilmaz MB,Refiker M,Guray Y,Guray U,Altay H,Demirkan B,Caldir V,Korkmaz S

更新日期：2007-02-01 00:00:00

abstract：:Osteoporosis results from a decrease in bone strength yielding increased susceptibility to fractures. Hip and spine fractures are a major cause of morbidity and mortality in the elderly population. With an increasingly ageing world population, early prevention of bone loss is essential for adequate control of this con...

journal_title：International journal of clinical practice

authors： Reginster JY,Malaise O,Neuprez A,Bruyere O

更新日期：2007-02-01 00:00:00

abstract：:Cases of transient global amnesia (TGA) seen by one consultant neurologist over a 4-year period (2002-2005 inclusive) were identified. Of 10 possible cases, eight fulfilled suggested diagnostic criteria. Five cases were seen as ward consultations, three in outpatient clinics; seven were seen in district general hospit...

journal_title：International journal of clinical practice

authors： Larner AJ

更新日期：2007-02-01 00:00:00

abstract：:The diagnosis of acute renal infarction (ARI) is often delayed or unrecognised because of its non-specific presentation and the rarity of the disease. We evaluated the clinical presentations, laboratory findings, underlying medical conditions and treatment of 18 Chinese patients with ARI who presented to the emergency...

journal_title：International journal of clinical practice

authors： Tsai SH,Chu SJ,Chen SJ,Fan YM,Chang WC,Wu CP,Hsu CW

更新日期：2007-01-01 00:00:00

abstract：:Leptospirosis is a re-emerging spirochetal zoonosis with a worldwide distribution affecting both animals and humans. The clinical syndromes may vary from a subclinical infection to a severe illness. Although it may potentially have a fulminant and fatal course, leptospirosis usually remains as an underdiagnosed cause ...

journal_title：International journal of clinical practice

authors： Dursun B,Bostan F,Artac M,Varan HI,Suleymanlar G

更新日期：2007-01-01 00:00:00

abstract：:This meta-analysis was undertaken to compare the effects of succinylcholine (SCH) and rocuronium (RCR) on endotracheal intubation (ETI) conditions. Eligible randomised controlled trials (RCTs) were identified via medline and a manual search of references. The frequencies of excellent and unacceptable ETI conditions in...

journal_title：International journal of clinical practice

authors： Karcioglu O,Arnold J,Topacoglu H,Ozucelik DN,Kiran S,Sonmez N

更新日期：2006-12-01 00:00:00

abstract：:Tumour markers are used for diagnosis, staging, evaluation of response to treatment, prognosis and detection of recurrences in clinical oncology. In this study, we aim to investigate the levels of insulin-like growth factor (IGF)-I and IGF-binding protein (IGFBP)-III in cases with oesophageal carcinoma. We investigate...

journal_title：International journal of clinical practice

authors： Yilmaz O,Eroglu A,Dag E,Karaoglanoglu N,Yilmaz A

更新日期：2006-12-01 00:00:00

abstract：:Sarcoidosis is a chronic disease with an unknown aetiology. Our aim was to evaluate the pattern of seasonality of stage 1 sarcoidosis subjects who had symptoms by all cases, by age and by both genders. In this study, we used Roger's test for cyclic variation to prove that this seasonal variation was more than chance. ...

journal_title：International journal of clinical practice

authors： Demirkok SS,Basaranoglu M,Akbilgic O

更新日期：2006-11-01 00:00:00

abstract：:The effects of diltiazem treatment on symptoms of chronic anal fissures and their long-term outcome were investigated. One hundred and twelve patients were supplied with 6-week course of 2% diltiazem cream for twice-daily topical application. The medical notes and extended follow-up by telephone for 112 patients were ...

journal_title：International journal of clinical practice

authors： Nash GF,Kapoor K,Saeb-Parsy K,Kunanadam T,Dawson PM

更新日期：2006-11-01 00:00:00

abstract：:Kaposi's sarcoma (KS) is a recognised complication following kidney transplantation, but the incidence varies according to the geographical area. Although it is a rare tumour, its incidence increases dramatically after solid-organ transplantation. The immunosuppressive medications reactivate human herpes virus 8, whic...

journal_title：International journal of clinical practice

authors： Kolhe N,Mamode N,Van der Walt J,Pattison J

更新日期：2006-11-01 00:00:00

abstract：:The aim of this study was to audit the preoperative administration of regular cardiac medication in general surgical patients and to determine if this can be improved with simple ward-based education. The notes and drug charts of 102 general surgical adult inpatients undergoing elective operations were analysed prospe...

journal_title：International journal of clinical practice

authors： Corfield LF,Trivedi PM,Wilson D

更新日期：2006-10-01 00:00:00

abstract：:Patients presenting to the emergency department with chest pain are evaluated by emergency physicians in hospitals without cardiology cover 24 h a day. The purpose of this study is to determine the consistency of electrocardiography (ECG) interpretation and chest pain likelihood classification between emergency physic...

journal_title：International journal of clinical practice

authors： Eken C,Goksu E,Eray O,Yalcinkaya S

更新日期：2006-10-01 00:00:00

abstract：:Overactive bladder (OAB) affects an estimated 49 million people in Europe, but only a minority receive appropriate treatment. Others are bothered by unacceptable levels of symptoms that severely impair their quality of life and represent a significant financial burden to themselves and to their healthcare providers. R...

journal_title：International journal of clinical practice

authors： Kirby M,Artibani W,Cardozo L,Chapple C,Diaz DC,De Ridder D,Espuna-Pons M,Haab F,Kelleher C,Milsom I,Van Kerrebroeck P,Vierhout M,Wagg A

更新日期：2006-10-01 00:00:00